Am i the only one who can run this in fullscreen no issues?

This build only includes a Direct3D renderer, and due to modifications made to it by 3D Realms, it is not possible to drag-and-drop renderers made for other UE1 games such as UT99 (e.g. the Glide renderer). The Voodoo5 has some support for Direct3D, so you may be able to try it out, but no guarantees.

Will this work with Voodoo 5?

Today is a great day for video game preservation.

Download the package (Rar)
Un-rar the files to a dukefolder (not your C:\ drive)
Unrar Duke.Nukem.Forever.2001-x0r_jmp.rar to a new folder you make called DNF2001 in the root of the drive.

You'll end up with a list of RAR's, readme, and a SFV file.
Duke.Nukem.Forever.2001-x0r_jmp.part01.rar is the start of the RAR file archive, extract it to DNF2001 folder.

Once you're done you'll have three file folders and a BUILDING.txt
August 21
October 26
Patches

Goto the Patches folder, copy the contents of Megapatch and D3DWrapper to October 26 Folder
Overwrite files when asked.

In October 26, there will be a Bat file, megabuild.bat, Run that, compiles the game.

Then goto system folder in October 26, find DukeForever.exe, goto properties, Compatibility, and set it to Xp Service Pack three. Apply. Don't Change other options.
Run dukeforever.exe,, it should open a XP window, and the cinematic should play along with the megadeth version of the Duke theme.

Once you get to the Menu, press F12 to open the console, and use Unreal Engine Console commands.

setres 1920x1080, this will freeze the game after applying, close Dukeforever.exe process using Task Manager, then restart the game, it will run 1920x1080 windowed.

Dookey Nookey
This build is old enough to drink.
Unfinished, but give it two-three years and the community will do the rest.

☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛ ☢♛

Based as fuck

A build of the game is already in the October 26 folder. To play it, copy the contents of the D3D8Wrapper and MegaPatch folders into the October 26 folder. Set your resolution and FOV through the console (F12) with the command setres ie. setres 1920x1080. Keep your game in windowed mode. If you get a black screen, try launching the game again or restart your PC.